UpToDate: “Patient Information” Edema swelling Beyond the basics. Tacrolimus Systemic: Potassium-Sparing Diuretics may enhance the hyperkalemic effect of Tacrolimus Systemic. No specific dosage recommendations for hepatic impairment; caution if using fixed combination with hydrochlorothiazide because of risk of precipitating hepatic coma. c d See Contraindications under Cautions. Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. amev.info cetirizine
Nonsteroidal Anti-Inflammatory Agents: May diminish the antihypertensive effect of Potassium-Sparing Diuretics. Nonsteroidal Anti-Inflammatory Agents may enhance the hyperkalemic effect of Potassium-Sparing Diuretics. Tell your doctor when you start any new drug, and discuss whether you should use additional reliable birth control. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. Used in fixed combination with hydrochlorothiazide for treatment of edema in patients who require a thiazide diuretic and in whom the development of hypokalemia cannot be risked and in patients who develop hypokalemia during hydrochlorothiazide monotherapy.
Canagliflozin: May enhance the hyperkalemic effect of Potassium-Sparing Diuretics. Canagliflozin may enhance the hypotensive effect of Potassium-Sparing Diuretics. This is a combination of 2 hormones: an ethinyl and a drospirenone. Dyrenium should be gradual. Does not competitively inhibit aldosterone; activity is independent of aldosterone concentrations.
Some MEDICINES MAY INTERACT with triamterene. Adrenal insufficiency: Avoid use of diuretics for treatment of elevated blood pressure in patients with primary adrenal insufficiency Addison disease. Chen HH, Anstrom KJ, Givertz MM et al. Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial. JAMA. When administering this drug with another diuretic, the doses of both drugs should be reduced. Onset of action is 2 to 4 hours after ingestion.
Only references cited for selected revisions after 1984 are available electronically. Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Bornstein 2016; Inder 2015. May cause a decreasing alkali reserve with the possibility of metabolic acidosis. Purpura; photosensitivity; rash; urticaria; necrotizing angiitis, vasculitis, cutaneous vasculitis; alopecia; exfoliative dermatitis; toxic epidermal necrolysis; erythema multiforme; Stevens-Johnson syndrome. Edema may develop during pregnancy due to comorbid pathology or the physiologic and mechanical consequences of pregnancy. b c d Diuretic therapy may be appropriate in the management of edema due to a pathologic cause manifesting during pregnancy. b c d However, dependent edema in pregnancy resulting from restriction of venous return by the gravid uterus may be treated by elevating the lower extremities and using support hose; diuretic therapy to lower intravascular volume is not appropriate in such cases. Check the sodium levels of food and drinks before you buy them. You can help balance your sodium by eating -rich foods like bananas and spinach, and drinking plenty of water. Could it be your lifestyle? Discuss the risks and benefits with your doctor. Maximum 300 mg daily. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use and wear protective clothing when outdoors. Does not inhibit carbonic anhydrase. Administer orally once daily. Some triamterene side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Principles of Internal Medicine, 19 th edition, McGraw-Hill Education, 2015. Houston BA, Kalathiya RJ, Kim DA et al. Volume Overload in Heart Failure: An Evidence-Based Review of Strategies for Treatment and Prevention. Mayo Clin Proc. Importance of taking drug after meals to help avoid stomach upset.
Diarrhea; dizziness or light-headedness when standing or sitting up; headache; loss of appetite; nausea. Used in fixed combination with hydrochlorothiazide for treatment of hypertension in patients who require a thiazide diuretic and in whom the development of hypokalemia cannot be risked and in patients who develop hypokalemia during hydrochlorothiazide monotherapy. Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, gout, high level of potassium in the blood, kidney disease including kidney stones liver disease, lupus. Cicci JD, Reed BN, McNeely EB et al. Acute decompensated heart failure: evolving literature and implications for future practice. Pharmacotherapy. Mild-to-moderate impairment: No dosage adjustment provided in manufacturer's labeling has not been studied. Hospira. Dopamine hydrochloride and 5% dextrose injection prescribing information. Lake Forest, IL; 2014 May. May be effective in some patients unresponsive to spironolactone; unlike spironolactone, diuretic effect of triamterene is independent of aldosterone concentrations. Renal clearances of triamterene, hydroxytriamterene sulfate, and hydrochlorothiazide may be reduced in geriatric patients receiving combined triamterene and hydrochlorothiazide therapy, principally as a result of age-related reductions in renal function. Muscle cramp or spasm; fever; anaphylactic reactions. Go AS, Bauman MA, Coleman King SM et al. An effective approach to high blood pressure control: a science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention. Hypertension. Triamterene may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use triamterene with caution. Yohimbine: May diminish the antihypertensive effect of Antihypertensive Agents. Triamterene should not be used in CHILDREN; safety and effectiveness in children have not been confirmed. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Gradually increase the amount of until you're getting at least 20 to 35 grams of fiber daily. biaxin
Oral: 10 to 40 mg 4 times a day. When triamterene is used in fixed combination with hydrochlorothiazide, consider the cautions, precautions, and contraindications associated with hydrochlorothiazide. Triamterene can lead to profound diuresis with fluid and electrolyte loss; close medical supervision and dose evaluation are required. Patients with heart failure, renal disease, or cirrhosis may be particularly susceptible to fluid and electrolyte abnormalities. Watch for and correct electrolyte disturbances; adjust dose to avoid dehydration. Diuretics. Analgesics Opioid may diminish the therapeutic effect of Diuretics. Tell your doctor if you develop any new symptoms. To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Symptoms may include lightheadedness; nausea; vomiting; weakness. Favre L, Glasson P, Vallotton MB. Reversible acute renal failure from combined triamterene and indomethacin. Ann Intern Med. DASH eating plan or a typical American diet. Results showed that reducing dietary sodium lowered blood pressure for both the DASH eating plan and the typical American diet. This drug may make you dizzy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. Take this by as directed by your doctor, with or without food, usually once daily. Pick a time of day that is easy for you to remember, and take your pill at the same time each day, 24 hours apart. Potassium loss has been reported during triamterene therapy in some patients with hepatic cirrhosis and may result in signs and symptoms of hepatic coma or precoma.
If this is the first time you are using this medication and you are not switching from another form of hormonal such as the patch, other take the first tablet in the pack on the first Sunday following the beginning of your menstrual period or on the first day of your period. If your period begins on a Sunday, begin taking this medication on that day. If you have any questions about Maxzide, please talk with your doctor, pharmacist, or other health care provider. UpToDate: “Patient information: Deep vein thrombosis Beyond the basics. Excreted in urine, primarily as 6- p-hydroxytriamterene. Take this by as directed by your doctor. May be taken after meals to decrease the risk of upset stomach. Diazoxide: May enhance the hypotensive effect of Blood Pressure Lowering Agents. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose. Take your next dose at the regular time. American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. cheap alternative to dipyridamole
Also, regularly. Moving your body will keep your bowels moving, too. L hyponatremia, hypochloremia, and increases in BUN may occur. May increase amantadine plasma levels and risk for adverse reactions. GlaxoSmithKline. Dyazide capsules prescribing information. Philadelphia, PA; 1999 Feb. ATPase, leading to potassium retention and decreased calcium, magnesium, and hydrogen excretion. We all need sodium. It plays an important part in regulating and fluid levels. But you only need a small amount. If you have too much in your system, your body holds in water. Table salt is one source of sodium, but we get more of it from processed food like lunch meat, crackers, chips, canned vegetables and soups, fast food, and even soft drinks. Do not consider Second Opinion as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. This medication may interfere with certain laboratory tests including parathyroid function possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Herbs Hypotensive Properties: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Tell your doctor if your condition does not improve or if it worsens for example, your increase. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. This medication should not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
But swelling in the hands and face could be a sign of a dangerous blood pressure problem called preeclampsia. This information should not be used to decide whether or not to take triamterene or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about triamterene. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to triamterene. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using triamterene. Some MEDICINES MAY INTERACT with Maxzide. WPC 003 for the 100-mg strength. This helps control the amount of in the body and urine. It works by making the urine more acidic. May occur in patients with or without history of allergy or bronchial asthma; cross-sensitivity with sulfonamides may also occur. Administration of Dyazide with a high-fat meal in healthy adults increased the average bioavailabilities of triamterene, 6- p-hydroxytriamterene, and hydrochlorothiazide by about 67, 50, and 17%, respectively; increased the peak concentrations of triamterene and its p-hydroxy metabolite; and delayed absorption of the active drugs by up to 2 hours. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Brimonidine Topical: May enhance the hypotensive effect of Blood Pressure Lowering Agents. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Patients receiving 25 mg of hydrochlorothiazide who become hypokalemic may be switched to Maxzide -25 mg 37. Its molecular weight is 253. This may not be a complete list of all interactions that may occur. Ask your health care provider if Maxzide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. IV: 20 to 100 mg every 1 to 2 hours over 1 to 2 minutes. buy cheap crestor mastercard usa
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Could it be something else? If you're constipated, it's often because there isn't enough water in your stool, a problem that occurs when too much fluid gets absorbed in your intestines. Diacerein: May enhance the therapeutic effect of Diuretics. Specifically, the risk for dehydration or hypokalemia may be increased. It is not known whether this drug passes into milk. Consult your doctor before -feeding. Use with caution in patients with impaired hepatic function. a Do not use in patients with severe hepatic disease. a Diuretic therapy in such patients should be initiated while the patient is hospitalized, because rapid alterations in fluid and electrolyte balance may precipitate hepatic coma. a Monitor serum potassium concentrations closely in patients with hepatic cirrhosis and administer potassium supplementation if required. a See Contraindications under Cautions. Serum bicarbonate concentrations consistently decreased; urinary pH increased slightly. Some products that may interact with this drug include: dofetilide, lithium, other drugs that may increase potassium levels such as spironolactone, amiloride, cyclosporine. Use triamterene as directed by your doctor. Check the label on the medicine for exact dosing instructions. Abrupt discontinuance may result in rebound kaliuresis; taper dosage gradually. Tell patient to take drug with food or milk and to report GI symptoms. Usually combined with a kaliuretic diuretic. While you're having an issue with constipation, limit foods that are high in fat and low in fiber, like cheese and other dairy products, processed foods, and meat. They can make constipation worse. Some medical conditions may interact with triamterene.
When this drug is used concomitantly with another diuretic or antihypertensive agent, the total daily dose of each agent should be lowered initially and then adjusted according to patient need. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may harm an unborn baby. Discuss the risks and benefits with your doctor. If you also take certain drugs to lower your cholesterol bile acid-binding resins such as cholestyramine or colestipol take this product at least 4 hours before or at least 4 to 6 hours after these medications. If any of these effects persist or worsen, notify your doctor promptly. Check your pressure regularly and tell your doctor if the results are high. The top number, which is the systolic blood pressure, corresponds to the pressure in the arteries as the heart contracts and pumps blood into the arteries. The bottom number, the diastolic pressure, represents the pressure in the arteries as the heart relaxes after the contraction. The diastolic pressure reflects the lowest pressure to which the arteries are exposed. May increase incidence of hypersensitivity reactions to allopurinol. Drink a lot of water when you take bulk laxatives. IV: If needed, repeat dose in 2 hours, after another 2 hours increase dose by 20 to 40 mg until an adequate diuresis. This dose should then be given once or twice a day. Journal of the American Medical Association reports that many are underdiagnosed. Hypertension is clearly a major public health problem. Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate. chloroquine
Although effective alone, often used in combination with other diuretics that act at different sites in the nephron. Serum potassium should be closely monitored during therapy with furosemide. Reduced clearance and increased risk of hyperkalemia; monitor serum potassium concentrations frequently. b c d See Hyperkalemia under Cautions. And on the subject of diet, water is important for preventing constipation, too. Try to drink at least 8 glasses of water a day. Oral bioavailabilities of triamterene and hydrochlorothiazide from Dyazide capsules are comparable to those of aqueous suspensions of the individual drugs, averaging 85 and 82%, respectively, for the fixed-dose formulation and 100 and 100%, respectively, for the suspensions. This product may cause your body to lose too much water and salt dehydration. Tell your doctor if your condition does not improve or if it worsens for example, your blood pressure readings increase. American Heart Association Task Force on practice guidelines. Circulation. Hospira. Dopamine hydrochloride prescribing information. Lake Forest, IL; 2014 Mar. May cause rapid progression into acute renal failure. Refer to adult dosing. In the management of hypertension, consider lower initial doses and titrate to response Aronow, 2011. Pholcodine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Pholcodine.
Patients with cirrhosis and splenomegaly may have marked hematologic abnormalities; these patients should have periodic blood studies and be observed for exacerbations of underlying liver disease. b See Megablastosis under Cautions. Caution patient to avoid sudden position changes to prevent orthostatic hypotension. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Potassium supplements: Avoid potassium supplements, potassium-containing salt substitutes, a diet rich in potassium, or other drugs that can cause hyperkalemia. UpToDate: “Patient information: Cirrhosis Beyond the basics. Maxzide may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Maxzide with caution. Severe sweating, diarrhea, or vomiting can increase the risk for lightheadedness or a serious loss of body water dehydration. Report prolonged diarrhea or vomiting to your doctor. To prevent dehydration, drink plenty of fluids unless your doctor directs you otherwise. Twice-daily administration of the fixed combination of triamterene and hydrochlorothiazide may increase risk of electrolyte imbalance and renal dysfunction. abilify purchase visa uk
AHFS Drug Information 2017. McEvoy GK, ed. Triamterene. ACE Inhibitors: Potassium-Sparing Diuretics may enhance the hyperkalemic effect of ACE Inhibitors. For the management of fluid retention associated with heart failure, experts state that diuretics should be administered at a dosage sufficient to achieve optimal volume status and relieve congestion without inducing an excessively rapid reduction in intravascular volume, which could result in hypotension, renal dysfunction, or both. If any of these effects persist or worsen, tell your doctor or promptly. Naftopidil: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Do not use for routine therapy in pregnant women with mild edema who are otherwise healthy. Molsidomine: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Some patients resistant to triamterene monotherapy may respond to such combined therapy. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased. Lederle Laboratories. Maxzide and Maxzide -25 MG tablets prescribing information. Pearl River, NY; 1988 May. There is no evidence that stone formation is increased in patients taking triamterene containing drugs. Here are a few effective constipation treatments.
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Most people get enough potassium by eating a well-. Talk to your doctor or about lifestyle changes that might benefit you. This product may increase your levels. Before using potassium or salt substitutes that contain potassium, consult your doctor or pharmacist. Special stockings or socks gently squeeze your lower legs to help keep your blood circulating. Discuss specific use of drug and side effects with patient as it relates to treatment. HCAHPS: During this hospital stay, were you given any medicine that you had not taken before?
Triamterene has been found in renal stones; use drug with caution in patients with histories of stone formation. America Society of Clinical Oncology: “Fluid Retention or Edema. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.
Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; burning, numbness, or tingling; confusion; decreased urination; drowsiness; dry mouth; excessive thirst; eye pain; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; mental or mood changes; muscle cramps, pain, or weakness; red, swollen, blistered, or peeling skin; restlessness; seizures; severe or persistent dizziness; shortness or breath; sluggishness; stomach pain; symptoms of high blood sugar eg, increased thirst, hunger, or urination; drowsiness; flushing; rapid breathing; fruit-like breath odor; tiredness or weakness; tremor; unusual bruising or bleeding; vision changes eg, decreased vision clearness; vomiting; yellowing of the skin or eyes.
Doses greater than 200 mg are rarely needed for treatment of edema. WellSpring Pharmaceutical Corporation. Dyrenium triamterene capsules prescribing information. Neptune, NJ; 2001 June. Gout: May cause elevation in uric acid.